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Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization
Background: Heart failure (HF) is a highly prevalent disorder for which disease mechanisms are incompletely understood. The discovery …
Albert Henry, María Gordillo-Marañón, Chris Finan, Amand F Schmidt, João Pedro Ferreira, Ravi Karra, Johan Sundström, Lars Lind, Johan Ärnlöv, Faiez Zannad, Anders Mälarstig, Aroon D Hingorani, R Thomas Lumbers
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The genomics of heart failure: design and rationale of the HERMES consortium
AIMS: The HERMES (HEart failure Molecular Epidemiology for Therapeutic targetS) consortium aims to identify the genomic and molecular …
R Thomas Lumbers, HERMES Consortium
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Life-Time Covariation of Major Cardiovascular Diseases: A 40 Year Longitudinal Study and Genetic Studies
Background - It is known that certain cardiovascular diseases (CVD) are associated, like atrial fibrillation (AF) and stroke. However, …
Lind Lars, Sundström Johan, Ärnlöv Johan, Ingelsson Martin, Henry Albert, Lumbers R. Thomas, Lampa Erik
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Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic
Circ Cardiovasc Qual Outcomes, 2020 Dec 20 [online]
Michail Katsoulis, Manuel Gomes, Alvina G. Lai, Albert Henry, Spiros Denaxas, Pagona Lagiou, Vahe Nafilyan, Ben Humberstone, Amitava Banerjee, Harry Hemingway, R. Thomas Lumbers
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Genetic and functional insights into the fractal structure of the heart
Nature, 2020 Aug 19 [online]
Hannah V. Meyer, Timothy J. W. Dawes, Marta Serrani, Wenjia Bai, Paweł Tokarczuk, Jiashen Cai, Antonio de Marvao, Albert Henry, R. Thomas Lumbers, Jakob Gierten, Thomas Thumberger, Joachim Wittbrodt, James S. Ware, Daniel Rueckert, Paul M. Matthews, Sanjay K. Prasad, Maria L. Costantino, Stuart A. Cook, Ewan Birney, Declan P. O’Regan
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Genetic and functional insights into the fractal structure of the heart
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
Nature Communications, 2020 Jan 09 [online]
Sonia Shah, Albert Henry, HERMES Consortium, R Thomas Lumbers
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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
The relationship between sleep duration, cognition and dementia: a Mendelian randomization study
International Journal of Epidemiology, 2019 May 07 [online]
Albert Henry, Michail Katsoulis, Stefano Masi, Ghazaleh Fatemifar, Spiros Denaxas, Dionisio Acosta, Victoria Garfield, Caroline E Dale
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The relationship between sleep duration, cognition and dementia: a Mendelian randomization study